The call was made yesterday in Dar es Salaam during the Agha Khan University (AKU) 14 convocation ceremony.
Makinda told the graduates that they have been educated for leadership and there is nothing more powerful than a leader and true leadership is not an office, it is an art.
"Your education has given you the skills to make change in our schools, hospitals and institutions, making them more responsible and effective" , Makinda told the graduates.
Speaking shortly after the ceremony, Abdallah Hoza, a graduate, said that they have been equipped and they have responsibilities to put into practice all that they had been taught.
Hoza promise to be a person that makes the difference in his office and be a person that people go to for professional guidance.
However, AKU has affirmed its commitment to continue contributing to Tanzania' social economic developed through the provision of high quality education for teachers and nurses.
Speaking at the ceremony, AKU president Firoz Rasul said "we are working hard to improve education and support the government's goal of up skilling primary school teachers".
The president said, they have helped to reduce hospital mortality, increase the number of women giving birth in health facilities and helped writing new nursing regulations.
The president said the university aims to improve the quality of life in the developing world and beyond through world class teaching, research and health care delivery.
Rasul added: " in partnership with the government and leading private sector organisations, the university works to build a world that values pluralism, encourages civil society initiatives and provides opportunity to all.
He said, their professional development programme had equipped nearly 3000 Tanzanian educators and teachers with new strategies for enhancing teaching and learning, benefiting well over 100,000 students.