GP Pak Stars raced to 143 runs, dropping eight wickets in the allotted 20 overs, after taking the crease first.
Hussain, the side's skipper, made his experience count given he was three runs short of a half-century, nailing three fours and three sixes.
Fellow batsmen, Sarfaraz Tare and Sultan Qureshi, also put solid knocks to show and posted 29 runs and 18 runs respectively.
Sheraz Khan, who opened the innings with Hussain, chipped in with 17 runs.
Saqib Ul Hassan, deployed as a middle-order batsman, somewhat boosted the club's score, notching 16 runs.
Much as Upanga SC B outfit's bowlers, Karim Kiseto, Shivan Kamania, and Arjan Rabadiya, put spirited showing, they could not prevent GP Pak Stars from ending the innings with a convincing total.
Kiseto ended with three wickets, fellow bowlers, Kamania and Rabadiya, notched two wickets apiece.
Notching 144 runs to emerge victorious proved to be tall order for the Upanga SC B squad, as the side's batting unit ended with 124 runs all out in 20 overs.
Opener Kiseto was the batsman with the most runs, notching 34 runs that consisted of two boundaries and a six.
This is the second title for the year 2021 for GP Pak Stars after winning the Kazim Nasser Memorial League (KNML) Division B 30 overs title.
Upanga SC B team was playing its third final of the 2021 season, having won the season's DC Cup's Division C top honour and DC KNML Division C title earlier in the year.
Sheraz Khan of GP Pak Stars was voted as the DC-MCC T20 Cup's Man of the Series, the tournament's best batsman award went to Muzammil Hussain from the same side.
Ayaz Mustafa of GP Pak Stars lifted the showpiece's best bowler prize, best wicketkeeper prize was won by Abbas Adamji of Annadil Burhani.
GP Pak Stars' Muzamill Hussain laid his hands on the final's Man of the Match prize to cap a fantastic outing for the club.
The tournament, organized by MCC in association with DC and Tanzania Cricket Association (TCA), was officially inaugurated in Dar es Salam in 2016.
The tournament, which was not held last year due to the coronavirus outbreak, involves 16 teams this time around.
The teams that have taken part in the tournament are Estim, Aga Khan SC, Shree Kutchi Leva Patel Sports Center (SKLPSC), Tamil Nadu Sports Club, GP, Alaf Aces, K&P Constructions outfit, and Caravans Cricket Club.
Lions Cricket Club, Union SC, Sandy's Super Strikers, Annadil Burhani, Dar Cricket Club (DCC), Dar Black Panthers, Upanga SC, and hosts, MCC, complete the list.
The 16 teams had been divided into four groups playing against each other in the round-robin phase, with the top two winners in each group qualifying for the quarterfinals.
The eight teams proceeded to the knockout stage and battled for progression to the semi-finals, with the last two reaching the finals.
The tournament had witnessed 31 matches being played during seven weeks, with the final due to be played at Leaders Club ground this month.
Other matches were played at the Dar es Salaam Gymkhana Club oval.
Balakrishna Foundation is the competition’s main sponsor. Other supporting sponsors include Estim Constructions Limited, Alliance Insurance Limited, Canara Bank Limited, Nida Textiles Limited, NTS- Bosch, Tanzanair Limited, Kivingu, Cosmos Group, Alliance Finance Limited, Eleven Agri Limited, and Rickshaw Travels Limited.
Unoplast Tanzania Limited, Honest Logistics Limited, Davis & Shirtliff Limited, Hitech Sai, METL Group, Abacus, UC Unity, ABC Emporio, Flashnet, A-One Products, and Bottlers Limited are also the co-sponsors.
Essar Life of Style, Gathani Tanzania Limited, Aurobindo, Xtreme Fitness, Target Brands, Ahead Africa Solutions, Regal Pharmaceuticals Limited, Unity Computers, Tanzindia Assurance Company Limited, and Wipro Technologies Tanzania Limited complete the co-sponsors list.