The Msimbazi Street-based team won their first CAF Champions League's group stage match, a 1-0 victory away to AS Vita Club in DR Congo.
Another victory will take them to the top of the table with six points. They have not lost in their last seven games across all competitions.
Didier Gomes da Rosa, Simba's head coach, has practically a full strength side to select from with captain John Bocco and Erasto Nyoni back from injury lay offs.
Jonas Mkude will likely be recalled in midfield for this fixture in Mzamiru Yasin’s place, whilst Paschal Wawa and Joash Ochieng should play at centre back again.
Simba will bank on a passionate home crowd support after the Confederation of African Football (CAF) approved their request to allow 30,000 fans to attend the game.
The club's information officer, Haji Manara, believes that they have the impetus to register maximum points as the prime target is to qualify for the quarter finals and beyond.
He said: “We defeated them in 1985 when they were the defending champions of CAF Club Cup Winners and the latest win was 1-0 when Meddie Kagere scored.''
“We are capable of beating them again. Everyone associated with Simba has that hope that we can win on Tuesday. From the players, the technical bench, officials and fans all are hopeful.''
“The players did not take off days granted after the Biashara United game because they needed to train and give Tanzanians an entertaining game against Al Ahly.”
“We accept that we are not at their levels but Simba always love playing big teams. We are psychologically prepared knowing that we have no other choice but to win on Tuesday.''
'' A win will take us closer to our target which is to qualify for the semi-final of the Champions League,” he concluded.
Meanwhile, Al Ahly will miss the service of Ali Maaloul, Taher Mohamed Taher, Walid Soliman, and Salah Mohsen, who have been ruled out due to injury, while Hussein El-Shahat is suspended.
On Saturday, they received good news, with defender Ayman Ashraf cleared fit for the Simba game after recovering from muscular injury.
In head-to-head stats, the two sides have met four times with each side claiming two wins.
Simba won the last meet played in Dar es Salam courtesy of a Meddie Kagere second half strike.