With eight NBC Premier League teams left in the draw, it meant that all-top-flight ties were produced for the quarterfinals.
As was the case last year, this season's quarterfinal draw was accompanied by the semi-final draw.
The quarterfinal ties will be played between April 1-3, with the winners going through to the semi-finals. The exact date and times of the fixtures are to be confirmed.
Simba SC has been drawn against Ihefu SC. These two sides are due to meet in the 2022/23 NBC Premier League match in Mbeya early next month
Ihefu SC has proved a gutsy opponent and will take inspiration from the outfit's victories over Azam FC and Yanga in the league this season.
Azam FC, winners of the Federation Cup in 2019, will host Mtibwa Sugar at Azam Complex Stadium.
Mwanza’s Mapinduzi FC was knocked out by Azam FC in the round of 16 while Mtibwa Sugar knocked out Kinondoni Municipal Council FC in the round of 16.
Azam FC reached the semi-finals of the Federation Cup last season before losing to Coastal Union and the former has generally been tough to beat in the tournament.
Mtibwa Sugar has been a mixed bag in the competition, going out in the first round in multiple editions but winning the tournament in 2018.
The winners of the quarterfinal encounter between Simba SC and Ihefu SC will face the winners of the duel between Azam FC and Mtibwa Sugar in the semi-finals.
Simba SC's bitter rivals Yanga, meanwhile, have a tough-looking tie at home to newly promoted Geita Gold FC as the Jangwani Street club continues the quest for another domestic double.
Yanga and Geita Gold FC met at this stage last season and were only separated by a penalty shootout after 90 minutes had ended in a 1-1 draw, the penalties ended with Yanga grabbing the victory.
The Jangwani Street outfit went on to defeat Simba SC and Coastal Union in the semi-finals and final to win the Federation Cup in the last campaign.
It is also a repeat of a league game that was played last week with Yanga coming from behind to win 3-1 against Geita Gold FC and extend their winning run to 11 league games.
The last quarterfinal tie will pit high-flying Singida Big Stars against Mbeya City FC, with the winners facing either Yanga or Geita Gold FC in the semi-finals.
The semi-finals will be played across the weekend of April 29 and May 1 in Lindi and Mtwara.
The final will be played at Mkwakwani Stadium in Tanga, with the showpiece taking place on June 3.
A trophy as well as medals for players, the technical bench, and 50m/- prize money will be handed over to the ASFC winner.
The showdown's winner moreover earns a ticket to represent the country in the CAF Confederation Cup next season.