After wining the toss Uluguru opted to field and bowled Upanga Warriors out for 155 runs in 38.2 overs of the match which was held at the University of Dar es Salaam venue.
Upanga Warriors shook off a wobbly start, which saw opening batsman Jumanne Mohamed face early dismissal with nine runs to his name, given fellow opening batsman Mohamed Omary scored 23 runs.
Promising all-rounder Aahil Jessani, as well, experienced a brief stay at the crease, notching 17 runs for the squad.
Experienced performers Kassim Nassor and Khalil Rehemtulla made their presence at the crease felt as they posted 33 runs and 23 runs respectively.
Uluguru's Salmin Yusuf ended with the best bowling figure, as he had four wickets and leaked 38 runs in 8.2 overs.
Agustine Meya, Kibwana Salum and Ally Mtanga as well had notable contribution with the ball, as they ad two wickets apiece.
Chasing 156 runs to win turned out to be a tall order for Uluguru, given they were skittled for 92 runs in 20.2 overs.
Jaffary Kanyita, who batted at number three, had the best innings given he notched 32 runs.
Kanyita's spell was cut short by Mohamed, with the batsman blasting two sixes and two fours.
Yusuf and Ivan Ismail were the other batsmen with double digit figures in the fruitless chase, notching 17 runs and 11 runs respectively.
The trio's efforts, though, failed to help Uruguru turn their fortunes around as team mates were sent back to the in quick succession.
Nassor as well had a good day with the ball, registering three wickets in five overs. Medium pacer Mohamed posted two wickets in four overs.
Kinondoni Development will lock horns with Amboni at the University of Dar es Salaam oval on Saturday, which will be the competition's only fixture in the day.
The competition, which is held under the auspices of TCA, has brought together outfits from Arusha, Dar es Salaam, Morogoro and Tanga.
In another development, efforts by TCA to develop the sport at the domestic level have gained momentum given the association has hosted a three-day introductory coaching course in Mwanza.
Hamis Abdallah, TCA Development Officer, is overseeing the course, which started on Wednesday and is set to climax today.
He is assisted by Rehemtullah, who also serves as TCA Development Coordinator.
The course, as disclosed by Rehemtullah, has brought together 14 primary and secondary schools teachers from across the region and is held at the Butimba Teachers College venue.